Vision & Mission
Our Vision
Heart failure is a significant global health issue with a generally poor long-term prognosis. To maintain heart homeostasis, cardiac cells are constantly adapting to their environment by remodeling their gene expression under both normal and disease conditions. This complex process involves not only the heart muscle cells (cardiomyocytes) but also numerous signaling pathways in their neighboring non-cardiomyocytes, as well as the crosstalk among these cells. An incomplete understanding of the coordination process hinders progress in developing effective treatments for cardiomyopathy and heart failure, making it a key area for ongoing research.
Our lab is committed to improving heart health in patients with heart failure that results from stress or disease-induced cardiomyopathy. We aim to bridge the gap between basic science and clinical application. To achieve this, we conduct innovative, interdisciplinary research using animal models and human induced pluripotent stem cells for disease modeling, and cutting-edge technologies such as ChIP-sequencing, single-cell RNA/ATAC sequencing, and Micro-C sequencing to explore and understand the multiple layers of epigenetic regulation involved in heart disease.
Mission
Our mission is to generate transformative knowledge that leads to the development of novel therapeutic strategies, ultimately improving patient outcomes. We are dedicated to fostering a collaborative and supportive environment that encourages creativity and rigorous scientific inquiry. Additionally, we are committed to nurturing the next generation of researchers in cardiovascular research, ensuring the continuation of impactful, innovative work in this critical field.